A bicyclic diterpenoid with a new 15,16-dinorlabdane carbon skeleton from Leonurus japonicus and its coagulant bioactivity.

نویسندگان

  • Fu Peng
  • Liang Xiong
  • Xiao-Mei Zhao
چکیده

A new 15,16-dinorlabdane diterpenoid 1 and a known labdane diterpenoid 2, together with three known ergosterols 3-5, were isolated from the EtOAc-soluble portion of the EtOH extract of Leonurus japonicus. Their structures were elucidated by physical and spectroscopic analysis. Compound 1 showed in vitro coagulant activity in the APTT, PT, TT, and FIB assays.

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عنوان ژورنال:
  • Molecules

دوره 18 11  شماره 

صفحات  -

تاریخ انتشار 2013